Tuesday, January 7, 2025

Nutrition Psychology. I asked Co-pilot and Claude about diet for health? Their replies are politically correct (but not equally consistent with science)

I continue my quest to understand how LLMs can be used to advance understanding of things. So I asked the Co-pilot and Clause about diet. Q 1: Which is the optimal diet for health? Q 2. Will the answer differ between studies conducted using food frequency questionnaires and Randomized control trials? Q 3. How healthy is meat? Q 4. How healthy is fat? Conclusion. Their reply about diet is very similar to the dietary guidelines (politically correct). But findings from paleo anthropology and current RCTs demonstrate on the one hand that animal source food, meat and fats, expanded our ancestors' brains, and on the other, that meat and saturated fats are not only safe to eat, but crucial for physical and mental health. It's important to note that since the introduction of dietary guidelines, health has deteriorated on a global scale. Ergo. Co-pilot's and Claude's summarized information is inconsistent with nutrition science.

12 pages.

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I continue my quest to understand how LLMs can be used to advance understanding of things. Since I slipped into nutritional psychology, it makes sense to ask Co-pilot and Clause about diet.

Question 1: Which is the optimal diet for health?

Co-pilot's response:

The optimal diet for health is one that provides a balanced intake of essential nutrients while promoting overall well-being. Here are some key principles:

1. Fruits and Vegetables: Aim for at least five portions of fruits and vegetables daily. They are rich in vitamins, minerals, antioxidants, and fiber, and are associated with a lower risk of chronic diseases.

2. Whole Grains: Include whole grains like oats, brown rice, and whole wheat. They are high in fiber and nutrients, which support digestive health and reduce the risk of chronic diseases.

3. Healthy Fats: Choose sources of healthy fats, such as avocado, nuts, seeds, and olive oil. These fats are beneficial for heart health and overall well-being.

4. Protein: Include a variety of protein sources, such as lean meats, fish, eggs, legumes, and dairy. Protein is essential for muscle repair and growth.

5. Limit Sugars and Salt: Keep free sugar intake to less than 10% of total energy intake (ideally less than 5%) and limit salt intake to less than 5 grams per day. This helps prevent obesity, diabetes, and hypertension.

6. Hydration: Stay well-hydrated by drinking plenty of water throughout the day. Proper hydration is essential for all bodily functions.

7. Balance and Moderation: Maintain a balanced diet and practice moderation. Avoid excessive consumption of processed foods, sugary drinks, and unhealthy fats.

8. Personalization: Consider individual needs, lifestyle, and cultural preferences when planning your diet. What works for one person may not work for another.

Claude's response:

Based on research, there isn't a single “optimal diet” that works best for everyone. What's optimal varies based on individual factors like:

1. Genetic makeup and metabolism

2. Age and gender

3. Activity level

4. Health conditions

5. Personal goals (weight management, athletic performance, etc.)

6. Food allergies or sensitivities

7. Cultural preferences

However, research has identified some common principles found in healthy dietary patterns:

Common Beneficial Elements:

- Abundant vegetables and fruits

- Whole grains

- Quality protein sources

- Healthy fats (like olive oil, avocados, nuts)

- Limited processed foods

- Adequate fiber intake

- Appropriate portion sizes

Several dietary patterns show positive health outcomes:

- Mediterranean diet

- Traditional Japanese diet

- Plant-based diets

- Nordic diet

- DASH diet

Key Principles for Any Healthy Diet:

- Sustainability (can maintain long-term)

- Nutritional adequacy

- Enjoyable and culturally appropriate

- Practical and affordable

- Promotes overall health markers

The most important factors tend to be:

- Consistency

- Overall dietary pattern rather than single foods

- Quality of food choices

- Personal adherence and satisfaction

I both cases, the answers are very broad and resemble the eat well plate and dietary guidelines.

Question 2. Will the answer differ between studies conducted using food frequency questionnaires and Randomized control trials?

Co-pilot's response:

Yes, the answers can differ between studies conducted using food frequency questionnaires (FFQs) and randomized controlled trials (RCTs).

Food Frequency Questionnaires (FFQs): Pros: FFQs are cost-effective and easy to administer, making them suitable for large-scale observational studies. They provide a long-term view of dietary habits.

Cons: FFQs rely on self-reported data, which can be subject to recall bias and inaccuracies. They may not capture short-term variations in diet and are sensitive to cultural and individual differences.

Randomized Controlled Trials (RCTs): Pros: RCTs are considered the gold standard for clinical research because they can establish cause-and-effect relationships. They involve controlled conditions and can provide more accurate and reliable data.

Cons: RCTs are often more expensive and time-consuming to conduct. They may not always reflect real-world conditions and can be limited by participant adherence to the intervention.

Key Differences:

Accuracy: RCTs generally provide more accurate and reliable data due to their controlled nature, while FFQs may be less precise due to self-reporting.

Scope: FFQs are better for assessing long-term dietary patterns, whereas RCTs can test specific dietary interventions over a shorter period.

Bias: FFQs are more prone to recall bias and inaccuracies, while RCTs minimize these biases through controlled conditions.

Claude's response:

Yes, there are significant differences between findings from food frequency questionnaires (FFQs) and randomized controlled trials (RCTs) in nutrition research:

Food Frequency Questionnaires:

- Observational in nature

- Rely on self-reported data

- Subject to recall bias

- Can track long-term habits

- Often have large sample sizes

- May show correlations but not causation

- More prone to confounding variables

- Usually less expensive to conduct

- Can suffer from under/over-reporting

Randomized Controlled Trials:

- Experimental design

- Direct measurement of outcomes

- More controlled environment

- Can establish causation

- Usually shorter duration

- Often smaller sample sizes

- More expensive to conduct

- Better control of variables

- More reliable for specific interventions

- May not reflect real-world eating patterns

These differences can lead to varying conclusions because:

1. FFQs might show associations that RCTs later disprove

2. RCTs might miss long-term effects that FFQs capture

3. FFQs can include lifestyle factors that RCTs control for

4. RCTs might show short-term benefits that don't translate to long-term outcomes

This is why nutrition researchers often consider evidence from both types of studies to form comprehensive conclusions about dietary effects on health.

Question 3. How healthy is meat?

Co-pilot's response:

The healthiness of meat depends on various factors, including the type of meat, preparation methods, and individual dietary needs. Here's a breakdown:

Health Benefits: Nutrient-Rich: Meat is a good source of high-quality protein, essential amino acids, vitamins (such as B12), iron, zinc, and other important nutrients.

Muscle Maintenance: Protein from meat helps maintain and build muscle mass, which is especially important for athletes and older adults.

Satiety: Meat can help you feel full and satisfied, which may aid in weight management by reducing overall calorie intake.

Potential Risks: Processed Meats: Consumption of processed meats (e.g., sausages, bacon) has been linked to an increased risk of certain cancers, heart disease, and other health issues due to high levels of sodium, nitrates, and preservatives.

Red Meat: High consumption of red meat (e.g., beef, pork, lamb) has been associated with increased risks of heart disease, colorectal cancer, and type 2 diabetes, particularly when consumed in large quantities or cooked at high temperatures.

Saturated Fats: Some meats, especially fatty cuts, are high in saturated fats, which can raise cholesterol levels and increase the risk of heart disease.

Tips for Healthier Meat Consumption:

Choose Lean Cuts: Opt for lean cuts of meat (e.g., skinless poultry, lean beef) to reduce saturated fat intake.

Limit Processed Meats: Minimize consumption of processed meats and choose fresh, unprocessed options whenever possible.

Balance: Incorporate a variety of protein sources, including plant-based proteins (e.g., beans, lentils, tofu), to diversify your diet.

Cooking Methods: Use healthy cooking methods like grilling, baking, steaming, or broiling instead of frying.

Claude's response:

The health effects of meat consumption depend on several factors. Here's what research shows:

Potential Benefits: - High-quality protein source - Rich in essential nutrients (B12, iron, zinc) - Complete amino acid profile - Can support muscle maintenance - Good source of bioavailable nutrients

Potential Concerns:

- Processed meats linked to increased health risks

- High consumption of red meat associated with certain diseases

- Cooking methods can affect health impact

- Quality and sourcing matter significantly

- Environmental contaminants can accumulate

Variables That Matter:

1. Type of Meat

- Red meat vs. white meat

- Processed vs. unprocessed

- Organ meats vs. muscle meat

- Wild vs. farmed

2. Preparation Method

- Grilling vs. slow cooking

- High-temperature cooking concerns

- Raw vs. cooked (safety issues)

3. Quality Factors

- Grass-fed vs. grain-fed

- Organic vs. conventional

- Presence of additives

- Animal welfare conditions

4. Individual Factors

- Personal genetics

- Digestive health

- Overall diet composition

- Activity level

Current research suggests:

- Moderate consumption of unprocessed meat can be part of a healthy diet

- Processed meats best limited or avoided

- Individual response varies significantly

- Context of overall diet matters more than any single food

Question 4. How healthy is fat?

Co-pilot's response:

Fat is an essential nutrient that plays several crucial roles in our body, but its healthiness depends on the type and amount of fat consumed. Here's a breakdown:

Healthy Fats: Monounsaturated Fats:

Found in: Olive oil, avocados, nuts, and seeds.

Benefits: Helps reduce bad cholesterol (LDL) levels, lowers the risk of heart disease, and provides essential fatty acids and vitamin E.

Polyunsaturated Fats:

Found in: Fatty fish (salmon, mackerel), walnuts, flaxseeds, and sunflower oil.

Benefits: Includes omega-3 and omega-6 fatty acids, which are vital for brain function, cell growth, and reducing inflammation. Omega-3s, in particular, are known for their heart-protective properties.

Less Healthy Fats:

Saturated Fats:

Found in: Red meat, butter, cheese, and other animal products.

Risks: High intake of saturated fats can raise bad cholesterol (LDL) levels and increase the risk of heart disease. It's generally recommended to limit saturated fat intake to less than 10% of total daily calories.

Trans Fats:

Found in: Partially hydrogenated oils, many fried foods, baked goods, and processed snacks.

Risks: Trans fats are the most harmful type of fat. They raise bad cholesterol (LDL) and lower good cholesterol (HDL), significantly increasing the risk of heart disease, stroke, and type 2 diabetes. It's best to avoid trans fats entirely.

Overall Recommendations:

Balance: Aim to include a variety of healthy fats in your diet while limiting the intake of saturated and trans fats.

Moderation: Fat is calorie-dense, so it's important to consume it in moderation to maintain a healthy weight.

Whole Foods: Focus on getting fats from whole food sources like nuts, seeds, fish, and avocados rather than processed foods.

Claude's response:

The health impact of fats depends heavily on the type and context. Here's what research shows:

Healthy Fats:

- Monounsaturated (olive oil, avocados)

- Omega-3s (fatty fish, flaxseeds)

- Some saturated fats (coconut oil, dairy)

Benefits include:

- Brain health support

- Hormone production

- Nutrient absorption

- Cell membrane function

- Anti-inflammatory effects

Less Healthy Fats:

- Trans fats (processed foods)

- Heavily processed vegetable oils

- Oxidized/rancid fats

Concerns include:

- Inflammation

- Cardiovascular risks

- Metabolic disruption

Key Factors:

1. Quality and Processing

- Source of the fat

- Processing methods

- Storage conditions

- Cooking temperature

2. Individual Response

- Genetic factors

- Current health status

- Overall diet composition

- Activity level

3. Context

- Total caloric intake

- Balance with other nutrients

- Timing of consumption

- Food combinations

Current Understanding:

- Fat isn't universally “good” or “bad”

- Quality matters more than quantity

- Individual response varies

- Balance is key

- Source and processing matter significantly

The responses from Co-pilot and Claude are broad and resemble dietary guidelines, which warn us from eating animal source food, like red meat and saturated fats, in favor of vegetarian options. The word balanced occurs eight times. Even so, like in dietary guidelines, there are animal source options included. The responses about methods, remarking differences between FFQs and RCTs, are interesting.

Nutrition is complex and often very ideological and political. Habits are also involved; we tend to sustain the same diet we started to eat when we were very young.

Humans belong to a genus - Homo and a species - Homo Sapiens. Our lineages go back at least six million years before the present (Mya; Pickford och Senut, 2001; Pickford, 2006; Pobiner, 2016). At that time they had small brains and ate only vegetarian options. 3.6 3.5 Mya, in the midst of Pliocen (5.33 – 2.58 Mya), findings show they ate bone marrow, which contains a number of hard-to-get micronutrients. As a consequence, their intestinal systems began to shrink and their brains expanded, from the occipital lobe and forward (Aiello och Dunbar, 1993; Aiello och Wheeler, 1995; Coolidge and Wynn, 2018; Hublin et al. 2015; Mann, 2018; McPherron et al. 2010; Pontzer et al 2016; Thompson et al. 2019).

2.8 (Mya), our genus – Homo – existed. They had a significantly larger brain and were upright thinkers (Kimbel och Villmoare, 2016; Mlodinov, 2015; Villmoare, 2018; Villmoare et al. 2015).

With a bigger brain, there was more room for thinking (Pringle, 2016). A marker for our species, which existed 320 000 years before the present (Hublin et al. 2017), is goal-oriented thinking, as one of many subset to the executive functions (Ardila, 2008, Ardila et al. 2018; Adornetti, 2016; Barkley, 2001; Gilbert och Wilson, 2007; Kaku, 2014; Pluck, Cerone and Villagomez-Pacheco, 2023; Suddendorf, Bulley, and Miloyan, 2018; Tomasello et al. 2005).

In 1908, the first formal education in dietetics is believed to have been offered at the College of Medical Evangelists (now Loma Linda University) in California. The name of the course  – “Hygienic Cooking and Baking”. In 1969, Loma Lina launched an ad about a Balanced diet.

Figure 3. The Seventh-Day Adventist church bought Loma Linda University, then promoted a 'balanced diet'. The current ad dates 1969.


Dietary guidelines occurred in the early 1980s, including the diet-heart hypothesis - that saturated fats cause cardiovascular disease. Since then, health has deteriorated on a global scale (Teicholz, 2023).

In 2006, the largest RCT on women's health was conducted to test the diet-heart hypothesis. The result rejected the hypothesis. On page 661, a special table is placed. It shows that women with previous health issues, who reduce their consumption of saturated fats, have an increased risk of contracting cardiovascular disease (Howard et al 2006). 10 years later, another large RCT tested the diet-heart hypothesis. Again, it was rejected (Ramsden et al 2016).

In 2019, the NutriRecs group published three papers where they used a method called GRADE to test the hypothesis that meat and processed meat is bad for health. The overall result - another rejection (Han et al. 2019; Johnston et al. 2019; Zeraatkar et al. 2019).

In fact, animal source food, meat and fats, are crucial, not only for children's physical and mental development (Adesogan et al. 2020; Allen, 2003; Balehegn et al. 2019, 2023), but also to sustain physical and mental health among adults (Calabrese et al 2024; Dobersek et al. 2023; Ede, 2019, 2022, 2024; Itkonen et al. 2020; Margara-Escudero et al. 2022; Pan et al. 2024; Tong et al. 2020; Ylilauri et al. 2019).

Conclusion. Co-pilot and Claude index information to provide a written answer. The reply about diet is very similar to the dietary guidelines. But findings from paleo anthropology and current RCTs demonstrate on the one hand that animal source food, meat and fats, expanded our ancestors' brains, and on the other, that meat and saturated fats are not only safe to eat, but crucial for physical and mental health. It's important to note that since the introduction of dietary guidelines, health has deteriorated on a global scale. Ergo. Co-pilot's and Claude's summarized information is inconsistent with nutrition science.

More about Nutrition Psychology (n=18):

2018. Nutrition psychology. Potatoes: The case for Reward sensation, GI/GL and Welfare diseases

2019. Nutrition psychology. What is the future for sustainable food? The case for prospective thinking (UH)

2019. Nutrition psychology. Can we have a Conversation about Food Preferences and Work Environment? An outlook from HELSUS survey on Vik campus (UH)

2020. Nutrition psychology. What’s the Prospect of sustainable Food? The Case for mental health (Abstract from presentation).

2022. Nutrition psychology. Is Alzheimer's Disease just another form of diabetes? The case of Finland

2023. Nutrition Psychology. A dietitian explains which non-dairy milk is best for you. A open letter to Marion, Benji and Nathaniel (Business Insider).

2023. Nutrition psychology. Nordic Nutrition Recommendations. The case for Continued influence bias, Groupthink, and dysrationalia.

2023. Nutrition psychology. Hur ska man välja mat i butiken? Medicinsk access (Swedish, but worth translating!)

2024. Nutrition psychology. Why are depression and loneliness big issues in Finland? (Why isn't entrepreneurial thinking more prevalent?).

2024. Nutrition psychology. Mental disorders may spread in young people’s social networks. That claim is probably misleading (inconsistent with scientific common knowledge).

2024. Nutrition psychology. Is women's relational aggressiveness a precursor to Alzheimer's? A comparison between Finland and Sweden.

2024. Nutrition psychology. Former mayor of Helsingfors suffered from cardio vascular disease (CVD). Is that explained by “natural stupidity" and will he accept nutrition science?

2024. Nutrition psychology. ADHD and Alzheimer's disease in Finland. Nurture is more likely explanation compared to nature.

2024. Nutrition psychology. Mental health and entrepreneurial thinking in Finland. The tension between enlightenment - tribal culture.

2024. Nutrition psychology. Meat, fat, and health. The case for Continued Influence bias.

2024. Nutrition psychology. Dementia (Alzheimer's disease). The case for intermittent fasting.

2024. Nutrition psychology. "A forgotten disease is raging in Finland, which takes away the work efficiency of working-age People" (Örn).

2024. Nutrition psychology. Mental erosion by malnutrition. The Case for Anterior and Subgenual Cingulate Cortex.

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